Education and Innovation in Cardiovascular Medicine

Gut microbe-dependent metabolite levels have prognostic value in heart failure

29-10-2014 • Tang et al., J Am Coll Cardiol. 2014
High levels of TMAO, a metabolite produced by gut microbiota from nutrients found in eggs and red meat, predicts higher mortality in stable HF patients. Read more
Webcast • Snapshot 2014

PCSK9 inhibition: Clinical Update 2014

Dr. Evan Stein, Cincinnati, USA, with an overview of phase III data with the PCSK9 inhibitor evolocumab as were presented in 2014 Watch

Hyperglycaemia appears harmful to the myocardium, also in prediabetics

28-10-2014 • Selvin E et al., Circulation. 2014
Both prediabetes and diabetes showed a higher incidence of subclinical myocardial damage, as assessed by hs-cTnT, associated with higher CV event risk. Read more
Webcast • Snapshot 2014

HoFH: New insights in prevalence and therapy

Dr. Kees Hovingh, Amsterdam, NL, shares some new insights in the prevalence of Familial Hypercholesterolemia and novel therapeutic options to lower LDL-c in this patient population Watch

Treating elderly AF patients with anticoagulation improves survival, more so than antiplatelets

23-10-2014 • Wändell PE et al., Age Ageing. 2014
Men and women with AF aged >75 years show increased survival with anticoagulants as compared to no treatment or treatment with antiplatelets. Not all pharmaceutical groups were associated with lower mortality and some sex differences were observed. Read more
News • 21-10-2014

AHA Scientific Statement on CVD risk factors in diabetic youth

The American Heart Association has issued a scientific statement on management of cardiovascular disease (CVD) risk factors in young people with diabetes mellitus type 1 or 2. Read more
Webcast • Snapshot 2014

What do novel diabetes drugs add to CV risk reduction?

Prof. Naveed Sattar, Glasgow, UK provides his view on the potential role of novel diabetes drugs in CV risk management Watch

Genetic predisposition to high LDL-c associated with aortic valve disease

27-10-2014 • Smith JG et al., JAMA 2014
Mendelian randomisation approach points at causal role for increased LDL-c in the development of aortic stenosis and presence of aortic valve calcium. Read more
E-Learning • Dr. Jeanine Roeters van Lennep

Homozygous FH: case report MTP inhibition

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Olive oil-supplemented Mediterranean diet can reverse metabolic syndrome

21-10-2014 • Babio N et al., CMAJ. 2014
Longer-term follow-up data suggest that a Mediterranean diet supplemented with extra-virgin olive oil is associated with reversal of metabolic syndrome, specifically regarding central obesity and high fasting plasma glucose. Read more

RCT refutes common believe that gradual weight loss has longer lasting effect than crash diet

20-10-2014 • Purcell et al., Lancet Diabetes & Endocrinology 2014
Regain of lost weight was similar in obese individuals randomised to a rapid or a gradual weight loss intervention. More participants in the rapid weight loss programme achieved weight loss of 12.5%. Read more
Webcast • Snapshot 2014

Is inflammation reduction key for targeting residual risk, beyond lowering LDL-c?

Dr. Paul Ridker, Boston, describes the different inflammatory pathways and ongoing clinical trials targeting inflammation Watch