Threshold for anticoagulant therapy the same for AF patients with or without renal failure

23-4-2014 • Friberg L et al., Eur Heart J. 2014
Renal failure is an independent risk factor for bleeding in atrial fibrillation, but patients likely benefit most from receiving the same treatment as AF patients without renal failure. Read more

Non-alcoholic fatty liver disease as an independent risk factor for CVD and type 2 diabetes

23-4-2014 • Byrne CD et al. Arterioscler Thromb Vasc Biol. 2014
Ectopic fat accumulation can result in insulin resistance. Early aggressive risk factor modification may prove beneficial to limit CVD risk. Read more

Even occasional use of NSAID or aspirin confers extra bleeding risk when on anticoagulation

23-4-2014 • Davidson BL et al., JAMA Intern Med. 2014
A clinically important increase in bleedings was observed in patients treated for VTE, who are simultaneously using anticoagulation and NSAIDs or aspirin. Read more
News • 22-4-2014

Call for wider appreciation of polypills for secondary prevention of CV disease

Two authors advocate the inclusion of fixed-dose combination therapy in the WHO Model List of Essential Medicins, to improve its access and use, to avoid premature death from CVD. Read more

Exercise training improves clinical outcome in women, but not men, with heart failure

17-4-2014 • Piña IL et al. JACC Heart Fail. 2014
In HF-ACTION, an exercise program plus optimal medical therapy (OMT) was associated with a lower risk of all-cause mortality and hospitalisation than OMT alone, in women, but not men with HF. Read more
News • 16-4-2014

EMA recommends against combined use RAS-inhibitors

ARBs, ACE-inhibitors and direct renin inhibitors better not combined, because of possible risks. Read more

Better control of atherosclerotic plaques during last decade

8-4-2014 • Van Lammeren GW et al. Circulation 2014
Over time, less unstable plaques and more frequently stable plaques were found in study of University Medical Center Utrecht Read more

Metabolic health affects risk of diabetes, but not of incident CVD in obese

22-4-2014 • Hinnouho GM et al., Eur Heart J. 2014
Metabolically healthy obese individuals have a lower risk of type 2 diabetes than the metabolically unhealthy obese, but the metabolically healthy remain at high risk for incident CVD. Read more
Webcast • VBWG - ACC 2014

Impact of new diabetes drugs on cardiovascular outcomes

Dr. Deepak Bhatt, Boston reviews multiple trials evaluating cardiovascular safety of new diabetes drugs such as DPP4 (EXAMINE & SAVOR-TIMI53 studies) and GLP1 agonists Watch

ACE inhibitors reduce CV morbidity and mortality in diabetics

17-4-2014 • Cheng J et al., JAMA Intern Med. 2014
Meta-analysis shows that ACEIs and ARBs differentially influence the risk of all-cause mortality, CV deaths and CV events in patients with DM. ACEIs reduce the risk, while ARBs do not. Read more

“Obesity paradox”: Better prognosis for overweight and obese patients with CVD

10-4-2014 • Lavie CJ, et al. JACC 2014
Overweight and obese patients with CV diseases have a better prognosis than do their leaner counterparts, largely in patients with low fitness. Read more
Webcast • ACC 2014

New British guidelines and risk calculator on CV Risk (JBS3)

JBS3, a novel approach for the prevention of CVD with 'lifetime CV risk' and 'heart age' and a new risk calculator. Chairman John E Deanfield highlights the key messages Watch

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